Research Article

In Effect of Poorna Chandrodayam Chendooram (metallic drug) on liver function, kidney function and lipid profile parameters of rats

Muthukumaran. P*, Pattabiraman. K, and Hazeena Begum

Published 12/11/2016 .
Email: kumaran.bio14@gmail.com




Author Affiliation

Department of Siddha Medicine, Faculty of Science, Tamil University, Vaakaiyur, Thanjavur - 613 010, Tamilnadu, India.


Article History

Received: Oct 2016 / Accepted: Oct2016/ Published: Dec 2016


How to Cite This Article

Muthukumaran, P., Pattabiraman, K., & Hazeena, B. (2016). Effect of Poorna Chandrodayam Chendooram (metallic drug) on liver function, kidney function and lipid profile parameters of rats. International Journal of Agricultural and Life Sciences, 2(4), 67-72. doi: 10.22573/spg.ijals.016.s12200068


Copyright

2016 Muthukumaran, P et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Competing Interests

The authors have declared that no competing interests exist.


Abstract

Poorna chandrodayam chendooram (PCM), a Siddha preparation which is used for its effect on liver function, kidney function and lipid profile after administrations into the biological system. The experimental animal model was of Male rats. Triglycerides (TG) Total cholesterol (TC), and low density lipoprotein (LDL) were decreased in experimental groups whereas high density lipoprotein (HDL) were slightly increased in male rats. The total protein and albumin content of plasma were increased very high significantly. In case of bilirubin, the decrease was negligible for rats. The serum glutamic pyruvic transaminase (sGPT), serum glutamic oxaloacetic transaminase (sGOT) and alkaline phosphatase (ALP) content in the plasma were decreased very high significantly in the experimental groups. Creatinine, and urea were decreased in male where only change of uric acid level was significant increased.